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serotoninergic 5-ht 2a r  (MultiTarget Pharmaceuticals)

 
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    Structured Review

    MultiTarget Pharmaceuticals serotoninergic 5-ht 2a r
    Affinity Values ( K i ) <xref ref-type= a of 1–11 at Human D 2 -like Receptor Subtypes and of 1–3 , 6 , 9 , Clozapine, and Olanzapine at Human D 1 R, 5-HT 1A R, 5-HT 2A R, and 5-HT 2C R" width="250" height="auto" />
    Serotoninergic 5 Ht 2a R, supplied by MultiTarget Pharmaceuticals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/serotoninergic+5-ht+2a+r/pmc08498988-54-19-42?v=MultiTarget+Pharmaceuticals
    Average 90 stars, based on 1 article reviews
    serotoninergic 5-ht 2a r - by Bioz Stars, 2026-08
    90/100 stars

    Images

    1) Product Images from "Scaffold Hybridization Strategy Leads to the Discovery of Dopamine D 3 Receptor-Selective or Multitarget Bitopic Ligands Potentially Useful for Central Nervous System Disorders"

    Article Title: Scaffold Hybridization Strategy Leads to the Discovery of Dopamine D 3 Receptor-Selective or Multitarget Bitopic Ligands Potentially Useful for Central Nervous System Disorders

    Journal: ACS Chemical Neuroscience

    doi: 10.1021/acschemneuro.1c00368

    Affinity Values ( K i ) <xref ref-type= a of 1–11 at Human D 2 -like Receptor Subtypes and of 1–3 , 6 , 9 , Clozapine, and Olanzapine at Human D 1 R, 5-HT 1A R, 5-HT 2A R, and 5-HT 2C R" title="... , Clozapine, and Olanzapine at Human D 1 R, 5-HT 1A R, 5-HT 2A R, ..." property="contentUrl" width="100%" height="100%"/>
    Figure Legend Snippet: Affinity Values ( K i ) a of 1–11 at Human D 2 -like Receptor Subtypes and of 1–3 , 6 , 9 , Clozapine, and Olanzapine at Human D 1 R, 5-HT 1A R, 5-HT 2A R, and 5-HT 2C R

    Techniques Used: Clone Assay

    Potency (EC 50 or IC 50 ) <xref ref-type= a and Efficacy (% Stimulation or % Inhibition) b Values of 3 , 6 , and 9 at D 1 R-D 4 R, 5-HT 1A R, 5-HT 2A R, and 5-HT 2C R" title="... , and 9 at D 1 R-D 4 R, 5-HT 1A R, 5-HT 2A R, ..." property="contentUrl" width="100%" height="100%"/>
    Figure Legend Snippet: Potency (EC 50 or IC 50 ) a and Efficacy (% Stimulation or % Inhibition) b Values of 3 , 6 , and 9 at D 1 R-D 4 R, 5-HT 1A R, 5-HT 2A R, and 5-HT 2C R

    Techniques Used: Inhibition, Functional Assay, cAMP Assay, Binding Assay



    Similar Products

    serotoninergic 5-ht 2a r  (MultiTarget Pharmaceuticals)
    90
    MultiTarget Pharmaceuticals serotoninergic 5-ht 2a r
    Affinity Values ( K i ) <xref ref-type= a of 1–11 at Human D 2 -like Receptor Subtypes and of 1–3 , 6 , 9 , Clozapine, and Olanzapine at Human D 1 R, 5-HT 1A R, 5-HT 2A R, and 5-HT 2C R" width="250" height="auto" />
    Serotoninergic 5 Ht 2a R, supplied by MultiTarget Pharmaceuticals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/serotoninergic+5-ht+2a+r/pmc08498988-54-19-42?v=MultiTarget+Pharmaceuticals
    Average 90 stars, based on 1 article reviews
    serotoninergic 5-ht 2a r - by Bioz Stars, 2026-08
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Affinity Values ( K i ) <xref ref-type= a of 1–11 at Human D 2 -like Receptor Subtypes and of 1–3 , 6 , 9 , Clozapine, and Olanzapine at Human D 1 R, 5-HT 1A R, 5-HT 2A R, and 5-HT 2C R" width="100%" height="100%">

    Journal: ACS Chemical Neuroscience

    Article Title: Scaffold Hybridization Strategy Leads to the Discovery of Dopamine D 3 Receptor-Selective or Multitarget Bitopic Ligands Potentially Useful for Central Nervous System Disorders

    doi: 10.1021/acschemneuro.1c00368

    Figure Lengend Snippet: Affinity Values ( K i ) a of 1–11 at Human D 2 -like Receptor Subtypes and of 1–3 , 6 , 9 , Clozapine, and Olanzapine at Human D 1 R, 5-HT 1A R, 5-HT 2A R, and 5-HT 2C R

    Article Snippet: Compounds 6 and 9 also display negligible D 1 R affinity but significantly lower K i values at the serotoninergic 5-HT 1A R, 5-HT 2A R, and 5-HT 2C R subtypes and, therefore, are characterized by a more balanced 5-HT/D 2 -like multitarget profile.

    Techniques: Clone Assay

    Potency (EC 50 or IC 50 ) <xref ref-type= a and Efficacy (% Stimulation or % Inhibition) b Values of 3 , 6 , and 9 at D 1 R-D 4 R, 5-HT 1A R, 5-HT 2A R, and 5-HT 2C R" width="100%" height="100%">

    Journal: ACS Chemical Neuroscience

    Article Title: Scaffold Hybridization Strategy Leads to the Discovery of Dopamine D 3 Receptor-Selective or Multitarget Bitopic Ligands Potentially Useful for Central Nervous System Disorders

    doi: 10.1021/acschemneuro.1c00368

    Figure Lengend Snippet: Potency (EC 50 or IC 50 ) a and Efficacy (% Stimulation or % Inhibition) b Values of 3 , 6 , and 9 at D 1 R-D 4 R, 5-HT 1A R, 5-HT 2A R, and 5-HT 2C R

    Article Snippet: Compounds 6 and 9 also display negligible D 1 R affinity but significantly lower K i values at the serotoninergic 5-HT 1A R, 5-HT 2A R, and 5-HT 2C R subtypes and, therefore, are characterized by a more balanced 5-HT/D 2 -like multitarget profile.

    Techniques: Inhibition, Functional Assay, cAMP Assay, Binding Assay